Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009934 | 0.91 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL8010106 | 0.88 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL8013752 | 0.80 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL6727325 | 0.75 | FAAH (0.44) | PPARA | |
| SCHEMBL389036 | 0.73 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL389037 | 0.73 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL8007402 | 0.72 | PPARG (0.86) | PPARGPPARA | |
| SCHEMBL4327346 | 0.72 | PPARA (0.42) | PPARA | |
| SCHEMBL13891652 | 0.71 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL5609071 | 0.70 | NR4A2 (0.39) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166049-A | Use of an antagonist of PPARα and PPARγ for the treatment of syndrome X | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-26 | — | — | US | disclosed |
| EP-0772605-A1 | BENZOXAZOLES AND PYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF THE TYPE II DIABETES | SMITHKLINE BEECHAM PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004260-A1 | BENZOXAZOLES AND PYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF THE TYPE II DIABETES | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |