Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188025 | 1.00 | TSHR (0.34) | TSHRDUT | |
| SCHEMBL12770685 | 0.95 | TSHR (0.35) | TSHRDUT | |
| SCHEMBL19090869 | 0.87 | TSHR (0.38) | TSHR | |
| SCHEMBL8329760 | 0.82 | USP2 (0.33) | DUT | |
| SCHEMBL14513909 | 0.82 | USP2 (0.33) | DUT | |
| SCHEMBL31644643 | 0.81 | DUT (0.35) | DUT | |
| SCHEMBL3206063 | 0.81 | DUT (0.35) | DUT | |
| SCHEMBL31644831 | 0.81 | DUT (0.35) | DUT | |
| SCHEMBL18099209 | 0.81 | DUT (0.36) | DUT | |
| SCHEMBL28427826 | 0.81 | ACE2 (0.36) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156905-A | Deoxy epothilones and intermediates utilized in the process for preparing epothilones | NOVARTIS AG (CH) | 2000-12-05 | — | — | US | disclosed |
| US-6043372-A | USEFUL CHEMICAL INTERMEDIATES FOR ANTICARCINOGENIC EPITHILONES | NOVARTIS AG (CH) | 2000-03-28 | — | — | US | disclosed |
| US-5969145-A | Process for the production of epothilones and intermediate products within the process | NOVARTIS AG (CH) | 1999-10-19 | — | — | US | disclosed |