Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801306 | 0.94 | KDM4E (0.44) | KDM4EL3MBTL1ATMNPSR1CYP1A2 | |
| SCHEMBL801485 | 0.94 | KDM4E (0.41) | KDM4EL3MBTL1ATMNPSR1CYP1A2 | |
| SCHEMBL801197 | 0.90 | NPSR1 (0.34) | KDM4EL3MBTL1ATMNPSR1CYP1A2 | |
| SCHEMBL801109 | 0.88 | KDM4E (0.39) | KDM4EL3MBTL1ATMNPSR1MEN1 | |
| SCHEMBL14923189 | 0.87 | KDM4E (0.48) | KDM4EL3MBTL1ATMNPSR1MEN1 | |
| SCHEMBL14923178 | 0.87 | KDM4E (0.48) | KDM4EL3MBTL1ATMNPSR1MEN1 | |
| SCHEMBL14923199 | 0.87 | KDM4E (0.48) | KDM4EL3MBTL1ATMNPSR1MEN1 | |
| SCHEMBL14923167 | 0.87 | KDM4E (0.48) | KDM4EL3MBTL1ATMNPSR1MEN1 | |
| SCHEMBL14923191 | 0.87 | KDM4E (0.48) | KDM4EL3MBTL1ATMNPSR1MEN1 | |
| SCHEMBL14923173 | 0.87 | KDM4E (0.48) | KDM4EL3MBTL1ATMNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2012-03-22 | — | — | US | disclosed |
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INPP5B, EZH2, PLCB3 | KDM4E 1186/4885L3MBTL1 1822/4885ATM 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.