SCHEMBL8015276

SCHEMBL8015276

CC[C@H]1CC[C@H](c2ccc(-c3ccc(Cl)cc3)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.51
DGAT1 O75907 1/20 0.43
SOAT1 P35610 1/20 0.43
LSS P48449 1/20 0.42
IDO1 P14902 1/20 0.41
SLC2A1 P11166 1/20 0.41
CYP2C9 P11712 2/20 0.41
ESR2 Q92731 2/20 0.41
HTR3A P46098 1/20 0.41
ESR1 P03372 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALDH1A1 P00352 2/20 0.39
KDM1A O60341 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
SRD5A1 P18405 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC6A3 Q01959 2/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8015280 1.00 DRD2 (0.51) DRD2DGAT1SOAT1LSSIDO1
SCHEMBL8453164 0.95 DRD2 (0.47) DRD2DGAT1SOAT1LSSIDO1
SCHEMBL8453175 0.95 DRD2 (0.47) DRD2DGAT1SOAT1LSSIDO1
SCHEMBL8453170 0.95 DRD2 (0.47) DRD2DGAT1SOAT1LSSIDO1
SCHEMBL10177543 0.94 DRD2 (0.56) DRD2LSSIDO1SLC2A1CYP2C9
SCHEMBL10982191 0.94 DRD2 (0.56) DRD2LSSIDO1SLC2A1CYP2C9
SCHEMBL11035814 0.91 ESR2 (0.47) DRD2DGAT1CYP2C9ESR2ESR1
SCHEMBL11035816 0.91 ESR2 (0.47) DRD2DGAT1CYP2C9ESR2ESR1
SCHEMBL7508508 0.89 DRD2 (0.51) DRD2LSSIDO1SLC2A1CYP2C9
SCHEMBL8029049 0.89 DRD2 (0.51) DRD2LSSIDO1SLC2A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704512-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-03-08 EP disclosed
EP-0704512-A1 A liquid crystal composition and a liquid crystal display element using the same Chisso Corporation (JP) 1996-04-03 EP disclosed