Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19192071 | 0.90 | GRIN2B (0.57) | GRIN2BMEN1RAB9AKMT2ABCHE | |
| SCHEMBL31630353 | 0.84 | ACHE (0.45) | MEN1RAB9AKMT2ABCHEACHE | |
| SCHEMBL31630016 | 0.84 | POLB (0.55) | MEN1RAB9AKMT2ABCHEACHE | |
| SCHEMBL663239 | 0.78 | GRIN2B (0.74) | GRIN2BMEN1RAB9AKMT2ABCHE | |
| Hydrochloric Acid SCHEMBL2550113 | 0.77 | MEN1 (0.78) | GRIN2BMEN1RAB9AKMT2ABCHE | |
| SCHEMBL13280563 | 0.75 | GRIN2B (0.59) | GRIN2BMEN1RAB9AKMT2ABCHE | |
| SCHEMBL16254267 | 0.75 | GRIN2B (0.59) | GRIN2BMEN1RAB9AKMT2ABCHE | |
| SCHEMBL25176271 | 0.75 | TSHR (0.58) | GRIN2BMEN1RAB9AKMT2ABCHE | |
| SCHEMBL1845568 | 0.75 | GRIN2B (0.54) | GRIN2BMEN1RAB9AKMT2ABCHE | |
| SCHEMBL15970177 | 0.75 | GRIN2B (0.54) | GRIN2BMEN1RAB9AKMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971893-A1 | CYANO SUBSTITUTED CYCLOALKANES | ZENECA LIMITED (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998043957-A1 | CYANO SUBSTITUTED CYCLOALKANES | ZENECA LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |