SCHEMBL8015665

SCHEMBL8015665

CCCc1ccc(-c2ccc(C(=O)O)cc2-c2cc(F)c(F)c(F)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.60
MPL P40238 5/20 0.52
RARA P10276 2/20 0.45
RARG P13631 1/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
MTOR P42345 1/20 0.45
KMT2A Q03164 1/20 0.45
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MCL1 Q07820 1/20 0.43
KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8025915 0.93 RARB (0.68) RARBMPLRARARARGMEN1
SCHEMBL8015669 0.92 RARB (0.54) RARBMPLRARARARGMEN1
SCHEMBL8025722 0.91 RARB (0.74) RARBMPLRARARARGMEN1
SCHEMBL28548977 0.85 RARB (0.80) RARBMPLRARARARGMEN1
SCHEMBL8025917 0.85 RARB (0.61) RARBMPLRARARARGMEN1
SCHEMBL8025725 0.84 RARB (0.67) RARBMPLRARARARGMEN1
SCHEMBL17108401 0.83 RARB (0.68) RARBMPLRARARARGMEN1
SCHEMBL15797758 0.80 RARB (0.67) RARBMPLRARARARGMEN1
SCHEMBL2744279 0.78 RARB (0.63) RARBMPLRARAMEN1ALDH1A1
SCHEMBL7722702 0.78 RARB (0.59) RARBMPLRARARARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704512-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-03-08 EP disclosed
EP-0704512-A1 A liquid crystal composition and a liquid crystal display element using the same Chisso Corporation (JP) 1996-04-03 EP disclosed