Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665 | 0.97 | — | — | |
| SCHEMBL8674191 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL11200771 | 0.94 | — | — | |
| SCHEMBL20838380 | 0.87 | LMNA (0.30) | TSHRLMNA | |
| SCHEMBL2076317 | 0.71 | — | — | |
| SCHEMBL8141220 | 0.69 | — | — | |
| SCHEMBL246786 | 0.67 | CYP1A2 (0.42) | LMNACYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL8105514 | 0.67 | — | — | |
| SCHEMBL115447 | 0.65 | CYP3A4 (0.33) | — | |
| Benzene SCHEMBL8015826 | 0.65 | TSHR (0.39) | TSHRLMNACYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |