Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.40 |
| ▸ | ITK | Q08881 | 10/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 2/20 | 0.36 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.36 |
| ▸ | MARK3 | P27448 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 2/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | NEK4 | P51957 | 2/20 | 0.36 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8144695 | 0.84 | F2 (0.47) | — | |
| SCHEMBL8016515 | 0.83 | ITK (0.44) | IDH1ITKACSL1MAP4K4CHEK2 | |
| SCHEMBL8017278 | 0.73 | ITK (0.51) | ITKACSL1MAP4K4CHEK2PRKCG | |
| SCHEMBL8027045 | 0.71 | F2 (0.45) | ITKACSL1MAP4K4CHEK2PRKCG | |
| SCHEMBL8015938 | 0.71 | ITK (0.40) | ITKMAP4K4CHEK2PRKCGPHKG2 | |
| SCHEMBL8027050 | 0.70 | ITK (0.45) | ITKACSL1MAP4K4CHEK2PRKCG | |
| SCHEMBL8026022 | 0.70 | MAPT (0.43) | ITKACSL1LMNAKMT2A | |
| SCHEMBL8028137 | 0.70 | CNR2 (0.48) | IDH1ACSL1CNR2KMT2ARORC | |
| SCHEMBL8029893 | 0.70 | F2 (0.46) | ACSL1CNR2LMNA | |
| SCHEMBL8029894 | 0.69 | ITK (0.43) | IDH1ITKACSL1MAP4K4CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |