Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029591 | 0.82 | ALDH1A1 (0.44) | MAPTKDM4ELMNAHSD17B10ACSL1 | |
| SCHEMBL8016135 | 0.78 | F2 (0.55) | KDM4ELMNAHSD17B10NPC1ALDH1A1 | |
| SCHEMBL8136672 | 0.78 | NPC1 (0.43) | MAPTKDM4ELMNAHSD17B10ACSL1 | |
| SCHEMBL8030134 | 0.78 | KMT2A (0.44) | KDM4ELMNAHSD17B10ACSL1NPC1 | |
| SCHEMBL8030127 | 0.77 | NPC1 (0.42) | MAPTKDM4ELMNAHSD17B10ACSL1 | |
| SCHEMBL8029593 | 0.77 | ACSL1 (0.42) | MAPTKDM4ELMNAHSD17B10ACSL1 | |
| SCHEMBL8016515 | 0.74 | ITK (0.44) | KDM4ELMNAHSD17B10ACSL1ITK | |
| SCHEMBL8017278 | 0.73 | ITK (0.51) | KDM4EACSL1NPC1ITK | |
| SCHEMBL8029893 | 0.73 | F2 (0.46) | LMNAHSD17B10ACSL1USP2SMN1; SMN2 | |
| SCHEMBL8027045 | 0.72 | F2 (0.45) | KDM4ELMNAACSL1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |