Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | RXRA | P19793 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | RARA | P10276 | 6/20 | 0.60 |
| ▸ | RARB | P10826 | 6/20 | 0.60 |
| ▸ | RARG | P13631 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | RXRB | P28702 | 4/20 | 0.60 |
| ▸ | RXRG | P48443 | 4/20 | 0.60 |
| ▸ | RORC | P51449 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012505 | 1.00 | CYP1A2 (0.77) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL2509311 | 1.00 | CYP1A2 (0.77) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL2509310 | 1.00 | CYP1A2 (0.77) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL6888824 | 0.89 | ALDH1A1 (0.77) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL954744 | 0.87 | CYP1A2 (1.00) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL954746 | 0.87 | CYP1A2 (1.00) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL15609136 | 0.87 | CYP1A2 (1.00) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL30568029 | 0.87 | CYP1A2 (0.61) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL4821672 | 0.86 | ALDH1A1 (0.77) | CYP1A2RXRAALDH1A1RARARARB | |
| SCHEMBL17052744 | 0.86 | ALDH1A1 (0.77) | CYP1A2RXRAALDH1A1RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966967-A | Compositions and methods of treating psoriasis with vinyligs of desmethyl retinoic acid | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1976-06-29 | — | — | US | claimed |
| US-6096765-A | Short contact treatment of acne with topical retinoids | BERSHAD SUSAN (US) | 2000-08-01 | — | — | US | disclosed |
| US-6083963-A | Short contact treatment of photoaging with topical retinoids | BERSHAD SUSAN (US) | 2000-07-04 | — | — | US | disclosed |
| US-6071923-A | Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases | BAR-ILAN UNIVERSITY (IL) | 2000-06-06 | — | — | US | disclosed |
| US-6048902-A | Short contact treatment of psoriasis with topical retinoids | BERSHAD, SUSAN | 2000-04-11 | — | — | US | disclosed |
| US-6043277-A | ADMINISTERING AS PROLIFERATION INHIBITORS, DIFFERENTIATING AGENTS | BAR-ILAN UNIVERSITY (IL) | 2000-03-28 | — | — | US | disclosed |
| US-6040342-A | Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases | BAR-ILAN UNIVERSITY (IL) | 2000-03-21 | — | — | US | disclosed |
| US-4642318-A | PSORIASIS | WOLFF KLAUS (AT) | 1987-02-10 | — | — | US | disclosed |