Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562821 | 0.86 | NOTUM (0.46) | NOTUMKDM1ABCHEKDM4EHDAC1 | |
| SCHEMBL3406623 | 0.86 | NOTUM (0.46) | NOTUMKDM1ABCHEKDM4EHDAC1 | |
| SCHEMBL6648372 | 0.86 | KDM1A (0.54) | NOTUMKDM1ABCHEKDM4EMEN1 | |
| SCHEMBL7004085 | 0.85 | KDM1A (0.50) | NOTUMKDM1ABCHEKDM4EMAPK1 | |
| SCHEMBL14222127 | 0.84 | KDM1A (0.46) | NOTUMKDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL30346095 | 0.84 | KDM1A (0.52) | NOTUMKDM1ABCHEMAPK1HDAC1 | |
| SCHEMBL3707225 | 0.84 | KDM1A (0.52) | NOTUMKDM1ABCHEMAPK1HDAC1 | |
| SCHEMBL29651255 | 0.83 | KDM1A (0.44) | NOTUMKDM1ABCHEKDM4EMEN1 | |
| SCHEMBL3695799 | 0.83 | KDM1A (0.44) | NOTUMKDM1ABCHEKDM4EMEN1 | |
| SCHEMBL5560266 | 0.82 | KDM1A (0.44) | NOTUMKDM1ABCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-07-27 | — | — | US | disclosed |
| WO-2009102574-A1 | QUINOLIZIDINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK & CO., INC. (US) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234920-A1 | Azirine Containing Compounds as Anti-Angiogenesis Agents and a Process for the Preparation Thereof | FLT1, PGF, KDR | NOTUM 2718/4885KDM1A 881/4885BCHE 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.