SCHEMBL8016288

SCHEMBL8016288

C=CCCC(CCC)C(C)(CC)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PLA2G2C Q5R387 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8006598 0.83 TSHR (0.33) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28936385 0.78 CHRM1 (0.38) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL18274540 0.75 SLC6A3 (0.35) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL11087654 0.72 PLA2G2C (0.30) PLA2G2C
SCHEMBL9710037 0.69 TSHR (0.35) TSHR
SCHEMBL1716224 0.69 CHRM1 (0.39) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28858244 0.68 GRIK1 (0.32)
SCHEMBL28647150 0.68 DPP4 (0.37) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL9655631 0.67 TSHR (0.32) SLC6A3TSHR
SCHEMBL9653986 0.67 TSHR (0.32) SLC6A3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811598-B1 5-Z-octenylesters,process for their preparation and their use HAARMANN & REIMER GMBH (DE) 2000-01-05 EP disclosed
EP-0811598-A1 5-Z-octenylesters,process for their preparation and their use HAARMANN & REIMER GMBH (DE) 1997-12-10 EP disclosed