Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053122 | 0.81 | MEN1 (0.38) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL9156326 | 0.80 | TDP1 (0.36) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL7820712 | 0.80 | TDP1 (0.42) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL9197708 | 0.79 | TDP1 (0.41) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL9154472 | 0.78 | KMT2A (0.41) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL3439097 | 0.78 | KMT2A (0.40) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL4714065 | 0.77 | TDP1 (0.52) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL13546218 | 0.76 | TDP1 (0.39) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL1696854 | 0.76 | TDP1 (0.47) | KMT2AALDH1A1MEN1TSHRTDP1 | |
| SCHEMBL9154376 | 0.76 | EPHX1 (0.43) | KMT2AALDH1A1MEN1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100264-A | 5H, 10H-imidazo [1,2-A] indeno [1,2-E] pyrazin-4-one derivatives, their preparation, their intermediates and medicaments containing them | RHONE-POULENC RORER, S.A. (FR) | 2000-08-08 | — | — | US | disclosed |
| US-5990108-A | USEFUL AS ANTAGONISTS OF THE ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (AMPA) RECEPTOR, ALSO KNOWN AS THE QUISQUALATE RECEPTOR, AND AS ANTAGONISTS OF THE N-METHYL-D-ASPARTATE (NMDA) RECEPTOR | RHONE POULENC RORER S.A. (FR) | 1999-11-23 | — | — | US | disclosed |