Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154472 | 0.94 | KMT2A (0.41) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL9156326 | 0.77 | TDP1 (0.36) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8016459 | 0.76 | KMT2A (0.39) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL9822530 | 0.74 | EPHX1 (0.50) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL6053122 | 0.70 | MEN1 (0.38) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL19803983 | 0.70 | MMP1 (0.36) | MMP1MMP2 | |
| SCHEMBL13004796 | 0.70 | EPHX1 (0.37) | EPHX1ALDH1A1KMT2ACTSSCTSK | |
| SCHEMBL3439097 | 0.70 | KMT2A (0.40) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8827712 | 0.69 | TDP1 (0.42) | EPHX1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7820712 | 0.69 | TDP1 (0.42) | EPHX1ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402312-B1 | P-substituted propane-phosphinic acid compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5190934-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0402312-A2 | P-substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1990-12-12 | — | — | EP | disclosed |