Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020135 | 0.78 | ALDH1A1 (0.40) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| SCHEMBL2384713 | 0.78 | NPSR1 (0.47) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| SCHEMBL239971 | 0.74 | KDM4E (0.50) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| SCHEMBL6831562 | 0.74 | ALDH1A1 (0.44) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| SCHEMBL28253909 | 0.74 | KDM4E (0.50) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| SCHEMBL465455 | 0.73 | NPSR1 (0.41) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| SCHEMBL30443421 | 0.72 | ALDH1A1 (0.43) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| Hydrochloric Acid SCHEMBL29269084 | 0.72 | KDM4E (0.48) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| Hydrochloric Acid SCHEMBL11409053 | 0.72 | KDM4E (0.48) | NPSR1TDP1CYP3A4PTGS2IDO1 | |
| SCHEMBL6832574 | 0.70 | NPSR1 (0.41) | NPSR1TDP1CYP3A4PTGS2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114174281-A | Degradation agent for cyclin dependent kinase 7(CDK7) and use thereof | 达纳-法伯癌症研究公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312899-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2021-02-02 | — | — | CN | disclosed |
| EP-0573182-B1 | Process for extracting metal values | AVECIA LTD (GB) | 2000-01-05 | — | — | EP | disclosed |
| US-5728853-A | AMIDO(BISTHIOPHOSHORYL) COMPOUNDS USEFUL FOR EXTRACTING METAL VALUES FROM AQUEOUS SOLUTIONS OF METAL SALTS | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| US-5557003-A | SOLVENT EXTRACTION OF ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |
| US-5502250-A | HYDROMETALLURGICAL PROCESS FOR EXTRACTING ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |
| US-5433855-A | Solvent extraction | ZENECA LIMITED (GB) | 1995-07-18 | — | — | US | disclosed |
| US-5393431-A | Solvent extraction using a aminobis(thiophosphoryl) compound | ZENECA LIMITED (GB) | 1995-02-28 | — | — | US | disclosed |
| EP-0573182-A1 | Process for extracting metal values | ZENECA LIMITED (GB) | 1993-12-08 | — | — | EP | disclosed |