Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.75 |
| ▸ | ACE | P12821 | 14/20 | 0.75 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033713 | 0.94 | MME (0.73) | MMEACECPA1ACE2TACR1 | |
| SCHEMBL8017397 | 0.93 | MME (0.65) | MMEACECPA1ACE2 | |
| SCHEMBL8032872 | 0.90 | MME (0.64) | MMEACECTSB | |
| SCHEMBL7565990 | 0.89 | MME (0.61) | MMEACECPA1ACE2TACR1 | |
| SCHEMBL7566002 | 0.89 | MME (0.61) | MMEACECPA1ACE2TACR1 | |
| SCHEMBL8027176 | 0.89 | MME (0.73) | MMEACECPA1ACE2 | |
| SCHEMBL8511466 | 0.88 | MME (0.77) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8028693 | 0.88 | MME (0.77) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL6439615 | 0.88 | MME (0.77) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL6439617 | 0.88 | MME (0.77) | MMEACECPA1ACE2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |