Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 1.00 |
| ▸ | ACE | P12821 | 13/20 | 1.00 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451466 | 0.94 | MME (0.88) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8027410 | 0.94 | MME (0.88) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8027181 | 0.93 | MME (0.86) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8027102 | 0.93 | MME (0.86) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8029453 | 0.92 | MME (0.84) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8451438 | 0.91 | MME (0.83) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8027294 | 0.91 | MME (0.83) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8017444 | 0.91 | MME (0.83) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL27547831 | 0.91 | MME (0.83) | MMEACECPA1ACE2HRH4 | |
| SCHEMBL8027482 | 0.89 | MME (0.80) | MMEACECPA1ACE2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |