Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.58 |
| ▸ | ACE | P12821 | 11/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017295 | 1.00 | MME (0.58) | MMEACEPPARGPPARDPPARA | |
| SCHEMBL8027609 | 0.96 | MME (0.66) | MMEACEPPARGPPARDPPARA | |
| SCHEMBL8030949 | 0.94 | MME (0.57) | MMEACEPPARGPPARDPPARA | |
| SCHEMBL8030944 | 0.94 | MME (0.57) | MMEACEPPARGPPARDPPARA | |
| SCHEMBL8448377 | 0.94 | MME (0.57) | MMEACEPPARGPPARDPPARA | |
| SCHEMBL8017192 | 0.92 | MME (0.70) | MMEACEPPARGPPARD | |
| SCHEMBL9007747 | 0.91 | MME (0.61) | MMEACEPPARGPPARD | |
| SCHEMBL8027626 | 0.90 | MME (0.65) | MMEACEPPARGPPARDPPARA | |
| SCHEMBL8523126 | 0.90 | MME (0.65) | MMEACEPPARGPPARDPPARA | |
| SCHEMBL8027621 | 0.90 | MME (0.65) | MMEACEPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |