⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412431 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL449640 | 0.75 | — | — | |
| SCHEMBL8883172 | 0.74 | — | — | |
| SCHEMBL3399566 | 0.74 | CETP (0.31) | — | |
| SCHEMBL826905 | 0.72 | TSHR (0.46) | — | |
| SCHEMBL5312660 | 0.72 | ABHD6 (0.33) | — | |
| SCHEMBL1738945 | 0.72 | — | — | |
| SCHEMBL321296 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL10412374 | 0.72 | HTT (0.32) | — | |
| SCHEMBL11183323 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6111110-A | Synthesis of benzo[f]quinolinones | ELI LILLY AND COMPANY (US) | 2000-08-29 | — | — | US | claimed |
| WO-1998018757-A1 | SYNTHESIS OF BENZO[F]QUINOLINONES | ELI LILLY AND COMPANY (US) | 1998-05-07 | — | — | WO | claimed |
| EP-0839807-A1 | Synthesis of benzo(f)quinolinones | ELI LILLY AND COMPANY (US) | 1998-05-06 | — | — | EP | claimed |
| US-6111110-A | Synthesis of benzo[f]quinolinones | ELI LILLY AND COMPANY (US) | 2000-08-29 | — | — | US | disclosed |
| EP-0969003-A2 | Process for the preparation of benzo[f]quinolinone derivatives and intermediates | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999065878-A1 | SYNTHESIS OF BENZO[F]QUINOLINONES | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |
| WO-1998018757-A1 | SYNTHESIS OF BENZO[F]QUINOLINONES | ELI LILLY AND COMPANY (US) | 1998-05-07 | — | — | WO | disclosed |
| EP-0839807-A1 | Synthesis of benzo(f)quinolinones | ELI LILLY AND COMPANY (US) | 1998-05-06 | — | — | EP | disclosed |