Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801486 | 0.98 | PPARG (0.40) | KDM4EATML3MBTL1PPARGNPSR1 | |
| SCHEMBL801165 | 0.94 | PPARG (0.38) | KDM4EPPARGNPSR1PPARAMAPT | |
| SCHEMBL801133 | 0.88 | KDM4E (0.47) | KDM4EATML3MBTL1NPSR1MAPT | |
| SCHEMBL801604 | 0.88 | PPARG (0.38) | KDM4EATML3MBTL1PPARGNPSR1 | |
| SCHEMBL801721 | 0.87 | PPARG (0.42) | KDM4EATML3MBTL1PPARGNPSR1 | |
| SCHEMBL801164 | 0.85 | PPARG (0.41) | KDM4EPPARGNPSR1PPARAMAPT | |
| SCHEMBL801302 | 0.85 | KDM4E (0.50) | KDM4EATML3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL801297 | 0.85 | KDM4E (0.56) | KDM4EATML3MBTL1NPSR1MAPT | |
| SCHEMBL801298 | 0.85 | KDM4E (0.56) | KDM4EATML3MBTL1NPSR1MAPT | |
| SCHEMBL30281357 | 0.85 | KDM4E (0.56) | KDM4EATML3MBTL1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| US-9278986-B2 | Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same | SK CHEMICALS CO., LTD. (KR) | 2016-03-08 | — | — | US | disclosed |
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2012-03-22 | — | — | US | disclosed |
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120068168-A1 | CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | INPP5B, EZH2, PLCB3 | KDM4E 1186/4885ATM 3758/4885L3MBTL1 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.