Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PER2 | O15055 | 5/20 | 0.40 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285336 | 0.78 | PER2 (0.40) | PER2CRY2 | |
| SCHEMBL9247177 | 0.78 | PER2 (0.40) | PER2CRY2 | |
| SCHEMBL13773401 | 0.74 | — | — | |
| SCHEMBL7463291 | 0.74 | — | — | |
| SCHEMBL14749793 | 0.74 | — | — | |
| SCHEMBL2195365 | 0.73 | PER2 (0.42) | PER2CRY2ALDH1A1LMNA | |
| SCHEMBL198156 | 0.73 | PER2 (0.39) | PER2CRY2 | |
| SCHEMBL7465403 | 0.71 | PER2 (0.40) | PER2CRY2GAAALDH1A1LMNA | |
| SCHEMBL2198451 | 0.70 | PER2 (0.54) | PER2CRY2 | |
| SCHEMBL564126 | 0.70 | APEX1 (0.66) | APEX1BLMTSHRPER2CRY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034083-A | AGRICULTURAL INSECTICIDE | NOVARTIS CORP. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5783704-A | INSECTICIDES; FOR AGRICULTURE PRODUCTS | NOVARTIS CORPORATION (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0737191-A1 | PYRIDINE DERIVATIVES AS PESTICIDES | Novartis AG (CH) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018123-A1 | PYRIDINE DERIVATIVES AS PESTICIDES | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |