Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325452 | 0.95 | GRIK1 (0.49) | ALDH1A1MAPK1SLC6A3TDP1LMNA | |
| SCHEMBL7636121 | 0.91 | ALDH1A1 (0.53) | ALDH1A1MAPK1SLC6A3TDP1LMNA | |
| SCHEMBL14519960 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPK1SLC6A3TDP1LMNA | |
| SCHEMBL7638634 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPK1SLC6A3TDP1LMNA | |
| SCHEMBL19105272 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPK1SLC6A3TDP1L3MBTL1 | |
| SCHEMBL6714506 | 0.85 | TDP1 (0.65) | ALDH1A1MAPK1TDP1LMNAL3MBTL1 | |
| SCHEMBL7635800 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL7644686 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNA | |
| SCHEMBL28554083 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPK1TDP1L3MBTL1KMT2A | |
| SCHEMBL22857444 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPK1SLC6A3TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1280561-A | Amidocarboxylic acid derivatives | SANKYO CO (JP) | 2001-01-17 | — | — | CN | disclosed |
| US-6118001-A | ANTICANCER AGENT; ANTIARTHRITIC AGENT | DARWIN DISCOVERY, LTD. (GB) | 2000-09-12 | — | — | US | disclosed |
| CN-1227540-A | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity | DARWIN DISCOVERY CO LTD (GB) | 1999-09-01 | — | — | CN | disclosed |