Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535809 | 0.82 | KMT2A (0.49) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL10306568 | 0.75 | MEN1 (0.54) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL27777630 | 0.74 | KMT2A (0.56) | KMT2ATDP1SLC6A2SLC6A3MEN1 | |
| SCHEMBL28392025 | 0.74 | MEN1 (0.50) | KMT2ATDP1MEN1LMNAPOLB | |
| SCHEMBL28389221 | 0.72 | MEN1 (0.51) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL28395027 | 0.72 | LMNA (0.49) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL28035571 | 0.72 | MEN1 (0.53) | KMT2ATDP1MEN1LMNATSHR | |
| SCHEMBL22584130 | 0.72 | MEN1 (0.53) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL28399527 | 0.71 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL23732386 | 0.71 | TSHR (0.49) | KMT2ATDP1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030655-A1 | WATER SOLUBLE PRODRUGS OF AZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-06-02 | — | — | WO | disclosed |