Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747882 | 0.92 | KIF11 (0.51) | KIF11CYP11B1CYP11B2RARARARB | |
| SCHEMBL8748031 | 0.91 | KIF11 (0.50) | KIF11CYP11B1CYP11B2RARARARB | |
| SCHEMBL8747993 | 0.90 | KIF11 (0.49) | KIF11CYP11B1CYP11B2RARARARB | |
| SCHEMBL8748211 | 0.90 | KIF11 (0.49) | KIF11CYP11B1CYP11B2RARARARB | |
| SCHEMBL8031328 | 0.89 | DAO (0.43) | KIF11FFAR1 | |
| SCHEMBL8748214 | 0.88 | DAO (0.42) | KIF11FFAR1 | |
| SCHEMBL10345128 | 0.86 | CYP17A1 (0.42) | KIF11CYP11B1CYP11B2RARARARB | |
| SCHEMBL8052160 | 0.86 | KIF11 (0.47) | KIF11CYP11B1CYP11B2FFAR1 | |
| SCHEMBL10723919 | 0.85 | CYP17A1 (0.41) | KIF11CYP11B1CYP11B2RARARARB | |
| SCHEMBL10723905 | 0.85 | CYP17A1 (0.41) | KIF11CYP11B1CYP11B2RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013198-A | LIQUID CRYSTALLINE COMPOUNDS MODIFIED TO HAVE A TRIFLUOROMETHYLPHENYL GROUP OR TRIFLUOROMETHOXYPHENYL GROUP AS EXAMPLE OF KNOWN TERMINAL SUBSTITUENT; CHEMICAL STABILITY, HIGH VOLTAGE HOLDING RATIO, GOOD UV STABILITY | CHISSO CORPORATION (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0761799-A1 | Liquid crystalline compound substituted with fluorine containing group, liquid crystal composition, and liquid crystal display device | Chisso Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |