Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.58 |
| ▸ | RARB | P10826 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778272 | 1.00 | PTPN11 (0.58) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL7778275 | 1.00 | PTPN11 (0.58) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL9647397 | 0.91 | PTPN11 (0.58) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL9143120 | 0.91 | PTPN11 (0.54) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL9486054 | 0.89 | PTPN11 (0.70) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL9485391 | 0.89 | PTPN11 (0.70) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL9485538 | 0.89 | PTPN11 (0.70) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL10340811 | 0.89 | PTPN11 (0.70) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL7875556 | 0.89 | PTPN11 (0.70) | PTPN11RARBTP53TSHRMCL1 | |
| SCHEMBL9485471 | 0.89 | PTPN11 (0.70) | PTPN11RARBTP53TSHRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153272-A | POLYMER SURFACE IN CONTACT WITH A LIQUID CRYSTAL MEDIUM IS EXPOSED TO POLARIZED LIGHT, WHEREBY A COVALENTLY BOUND ANISOTROPIC COMPONENT OF THE POLYMER SURFACE ALIGNS IN RESPONSE TO THE POLARIZED LIGHT | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0387059-B1 | Process of aligning liquid crystal media | HERCULES INC (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5589100-A | LIQUID CRYSTAL DISPLAY SUBSTRATES WITH ARYLAZO OR POLYARYLAZO DYES | HERCULES INCORPORATED (US) | 1996-12-31 | — | — | US | disclosed |
| US-5389285-A | Liquid crystal coupled dichroic dyes | HERCULES INCORPORATED (US) | 1995-02-14 | — | — | US | disclosed |
| US-5326865-A | Arylazo and poly(arylazo) dyes having at least one core radical selected from naphthyl or anthracyl and having at least one 2,3-dihydro-1,3-dialkyl perimidine substituent | HERCULES INCORPORATED (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0460504-B1 | Dichroic azo dyes | HERCULES INC (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5097029-A | Hydrolysis, alkylation, intermediates for azo dyes | HERCULES INCORPORATED (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0460504-A1 | Dichroic azo dyes | HERCULES INCORPORATED (US) | 1991-12-11 | — | — | EP | disclosed |
| US-5032009-A | Polarized light exposure | HERCULES INCORPORATED (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0432735-A2 | Liquid crystal coupled dichroic dyes | HERCULES INCORPORATED (US) | 1991-06-19 | — | — | EP | disclosed |
| EP-0406812-A2 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4974941-A | Process of aligning and realigning liquid crystal media | HERCULES INCORPORATED (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0387059-A2 | Process of aligning liquid crystal media | HERCULES INCORPORATED (US) | 1990-09-12 | — | — | EP | disclosed |