Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.58 |
| ▸ | RARB | P10826 | 4/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018495 | 0.91 | PTPN11 (0.58) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL7778272 | 0.91 | PTPN11 (0.58) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL7778275 | 0.91 | PTPN11 (0.58) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL7875556 | 0.89 | PTPN11 (0.70) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL9486054 | 0.89 | PTPN11 (0.70) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL9485471 | 0.89 | PTPN11 (0.70) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL10340811 | 0.89 | PTPN11 (0.70) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL9485538 | 0.89 | PTPN11 (0.70) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL9640138 | 0.89 | PTPN11 (0.70) | PTPN11RARBPLA2G4BTP53TSHR | |
| SCHEMBL9485391 | 0.89 | PTPN11 (0.70) | PTPN11RARBPLA2G4BTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244129-B1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTALLINE COMPOSITION | AJINOMOTO CO., INC. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4880561-A | Optically active compound and liquid crystalline composition | AJINOMOTO CO., INC. (JP) | 1989-11-14 | — | — | US | disclosed |