Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008318 | 0.81 | GRM2 (0.52) | GRM5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15319276 | 0.79 | KMO (0.48) | KMOTSHRSLC6A3SRD5A2GRM5 | |
| SCHEMBL15318986 | 0.79 | KMO (0.51) | KMOTSHRSLC6A3SRD5A2MEN1 | |
| SCHEMBL15319135 | 0.79 | KMO (0.51) | KMOTSHRSLC6A3SRD5A2MEN1 | |
| SCHEMBL15319336 | 0.79 | KMO (0.51) | KMOTSHRSLC6A3SRD5A2MEN1 | |
| SCHEMBL15319227 | 0.78 | KMO (0.48) | KMOTSHRSLC6A3SRD5A2GRM5 | |
| SCHEMBL18519811 | 0.78 | KMO (0.53) | KMOTSHRSLC6A3SRD5A2HPGD | |
| SCHEMBL21448810 | 0.78 | KMO (0.53) | KMOTSHRSLC6A3SRD5A2HPGD | |
| SCHEMBL21448805 | 0.78 | KMO (0.53) | KMOTSHRSLC6A3SRD5A2HPGD | |
| SCHEMBL16506453 | 0.77 | KMO (0.47) | KMOTSHRSLC6A3SRD5A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |