Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036763 | 0.92 | PDK2 (0.43) | PDK2CYP1A2CYP2C19KMT2ANPC1 | |
| SCHEMBL17427066 | 0.87 | PDK2 (0.35) | PDK2CYP1A2CYP2C19KMT2ANPC1 | |
| SCHEMBL80388 | 0.87 | PDK2 (0.40) | PDK2CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL81168 | 0.86 | PDK2 (0.38) | PDK2CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL82020 | 0.85 | PDK2 (0.37) | PDK2CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL80220 | 0.82 | PDK2 (0.39) | PDK2CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL80361 | 0.82 | GABRG2 (0.39) | PDK2CYP1A2CYP2C19KMT2AGABRG2 | |
| SCHEMBL17427067 | 0.81 | ABCG2 (0.35) | PDK2CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL68937 | 0.81 | PDK2 (0.57) | PDK2CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL80873 | 0.81 | GABRG2 (0.40) | PDK2CYP1A2CYP2C19KMT2AGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8129899-B1 | Azafluorene derivative and organic light-emitting device using the derivative | CANON KABUSHIKI KAISHA (JP) | 2012-03-06 | — | — | US | disclosed |