⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15238069 | 0.75 | — | — | |
| SCHEMBL467116 | 0.73 | — | — | |
| SCHEMBL270833 | 0.73 | — | — | |
| SCHEMBL3126251 | 0.71 | — | — | |
| SCHEMBL27872834 | 0.71 | — | — | |
| SCHEMBL1273762 | 0.71 | — | — | |
| SCHEMBL15415496 | 0.70 | SLC6A2 (0.31) | — | |
| SCHEMBL5967575 | 0.69 | GHSR (0.33) | — | |
| SCHEMBL12534333 | 0.68 | — | — | |
| SCHEMBL361757 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5117367-A | — | — | None | — | — | JP | disclosed |
| EP-3083592-A2 | SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES AND THEIR USE AS ALPHA-2C ADRENORECEPTOR ANTAGONISTS | Bayer Pharma Aktiengesellschaft (DE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015091414-A2 | SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2000042133-A1 | IMPROVED FUEL COMPOSITIONS | INFINEUM INTERNATIONAL LTD (GB) | 2000-07-20 | — | — | WO | disclosed |
| JP-H05117367-A | EPOXY RESIN COMPOSITION CONTAINING 4-METHYL-2-MORPHOLINONE AS CURING AGENT | TEXACO CHEM CO | 1993-05-14 | — | — | JP | disclosed |
| EP-0207199-A1 | Selective absorbtion of sulfur dioxide from gases containing sulfur dioxide and carbon dioxide | THE DOW CHEMICAL COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |