Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.64 |
| ▸ | RELA | Q04206 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | ACR | P10323 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990105 | 1.00 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9711357 | 1.00 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL8990116 | 1.00 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL8018492 | 1.00 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9766506 | 1.00 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL7778269 | 1.00 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9796851 | 0.97 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9200762 | 0.97 | LMNA (0.64) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL10358904 | 0.94 | NPC1 (0.58) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9812246 | 0.93 | NPC1 (0.57) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851302-B2 | Metal organic liquid crystal dyes | GAUZY LTD. (IL) | 2020-12-01 | — | — | US | disclosed |
| EP-3209748-B1 | METAL ORGANIC LIQUID CRYSTAL DYES | GAUZY LTD (IL) | 2020-05-06 | — | — | EP | disclosed |
| US-20170355908-A1 | METAL ORGANIC LIQUID CRYSTAL DYES | GAUZY LTD. (IL) | 2017-12-14 | — | — | US | disclosed |
| US-20170336663-A1 | BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF | GAUZY LTD. (IL) | 2017-11-23 | — | — | US | disclosed |
| EP-3215587-A1 | BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF | Gauzy Ltd. (IL) | 2017-09-13 | — | — | EP | disclosed |
| EP-3209748-A1 | METAL ORGANIC LIQUID CRYSTAL DYES | Gauzy Ltd (IL) | 2017-08-30 | — | — | EP | disclosed |
| WO-2016071908-A1 | BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF | GAUZY LTD. (IL) | 2016-05-12 | — | — | WO | disclosed |
| US-6153272-A | POLYMER SURFACE IN CONTACT WITH A LIQUID CRYSTAL MEDIUM IS EXPOSED TO POLARIZED LIGHT, WHEREBY A COVALENTLY BOUND ANISOTROPIC COMPONENT OF THE POLYMER SURFACE ALIGNS IN RESPONSE TO THE POLARIZED LIGHT | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2000-11-28 | — | — | US | disclosed |
| US-5989451-A | Compounds and methods for doping liquid crystal hosts | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1999-11-23 | — | — | US | disclosed |
| WO-1998034995-A1 | COMPOUNDS AND METHODS FOR DOPING LIQUID CRYSTAL HOSTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1998-08-13 | — | — | WO | disclosed |
| US-4974941-A | Process of aligning and realigning liquid crystal media | HERCULES INCORPORATED (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0288813-B1 | USE OF OPTICALLY ACTIVE 1,3-DIOXOLANE-4-CARBOXYLIC-ACID ESTERS AS DOPING AGENTS IN LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |
| EP-0248335-B1 | CHIRAL ESTERS OF ALPHA-SUBSTITUTED CARBOXYLIC ACIDS AND MESOGENEOUS PYRIMIDINE-5-YL-PHENOLS, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL PHASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | disclosed |
| EP-0387059-A2 | Process of aligning liquid crystal media | HERCULES INCORPORATED (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4891151-A | Liquid-crystalline phenylpyrimidinyl cyclohexanecarboxylates having a smectic phase, a process for their preparation, and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |
| US-4855429-A | HIGH VALUES OF SPONTANEIOUS POLARIZATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0308794-A2 | Liquid crystal phenyl pyrimidine ester of cyclohexane-carboxylic acid with a smectic phase in liquid crystal mixtures and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-29 | — | — | EP | disclosed |
| EP-0292954-A2 | Use of optically active oxirane-2-carboxylic acid esters as dopants in liquid crystal mixtures containing them and new optically active oxirane-2-carboxylic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0288813-A1 | Use of optically active 1,3-dioxolane-4-carboxylic-acid esters as doping agents in liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-02 | — | — | EP | disclosed |
| EP-0248335-A2 | Chiral esters of alpha-substituted carboxylic acids and mesogeneous pyrimidine-5-yl-phenols, and their use as dopants in liquid-crystal phases | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-09 | — | — | EP | disclosed |