Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019125 | 1.00 | RARB (0.36) | RARBRARARARGNAAAS1PR1 | |
| SCHEMBL8017395 | 0.88 | RARB (0.40) | RARBRARARARGS1PR1PDE5A | |
| SCHEMBL8017398 | 0.88 | RARB (0.40) | RARBRARARARGS1PR1PDE5A | |
| SCHEMBL8015296 | 0.85 | PDE5A (0.34) | RARBRARANAAAPDE5A | |
| SCHEMBL8015298 | 0.85 | PDE5A (0.34) | RARBRARANAAAPDE5A | |
| SCHEMBL8021447 | 0.79 | RARB (0.42) | RARBRARARARGS1PR1PDE5A | |
| SCHEMBL7766387 | 0.79 | RARB (0.42) | RARBRARARARGS1PR1PDE5A | |
| SCHEMBL8021444 | 0.79 | RARB (0.42) | RARBRARARARGS1PR1PDE5A | |
| SCHEMBL7766389 | 0.79 | RARB (0.42) | RARBRARARARGS1PR1PDE5A | |
| SCHEMBL8433451 | 0.79 | CYP3A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |