Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015298 | 1.00 | PDE5A (0.34) | PDE5AHCRTR2RARARARBNAAA | |
| SCHEMBL8019125 | 0.85 | RARB (0.36) | PDE5ARARARARBNAAA | |
| SCHEMBL8019123 | 0.85 | RARB (0.36) | PDE5ARARARARBNAAA | |
| SCHEMBL9008457 | 0.84 | PDE5A (0.35) | PDE5ARARARARBGCGR | |
| SCHEMBL9008454 | 0.84 | PDE5A (0.35) | PDE5ARARARARBGCGR | |
| SCHEMBL7758913 | 0.76 | PDE5A (0.36) | PDE5ARARARARBGCGR | |
| SCHEMBL19393879 | 0.76 | RARA (0.37) | RARARARBNAAA | |
| SCHEMBL7758916 | 0.76 | PDE5A (0.36) | PDE5ARARARARBGCGR | |
| SCHEMBL9754192 | 0.76 | HCRTR2 (0.43) | HCRTR2 | |
| SCHEMBL9754194 | 0.76 | HCRTR2 (0.43) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |