Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 8/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019181 | 0.81 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL11329429 | 0.80 | AR (0.42) | SRD5A1SRD5A2AR | |
| SCHEMBL11329447 | 0.80 | AR (0.42) | SRD5A1SRD5A2AR | |
| SCHEMBL27369411 | 0.77 | AR (0.42) | SRD5A1SRD5A2AR | |
| SCHEMBL23378235 | 0.77 | AR (0.44) | SRD5A1SRD5A2AR | |
| SCHEMBL7515861 | 0.76 | MEN1 (0.40) | SRD5A1AR | |
| SCHEMBL7515870 | 0.76 | MEN1 (0.40) | SRD5A1AR | |
| SCHEMBL21807712 | 0.76 | AR (0.45) | SRD5A2AR | |
| SCHEMBL8898529 | 0.76 | AR (0.45) | SRD5A2AR | |
| SCHEMBL7193192 | 0.75 | AR (0.61) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664812-B1 | 17-BETA-ARYL ESTER CARBOXYLATES OF 4-AZA-5-ALPHA-ANDROSTANE-3-ONES | MERCK & CO INC (US) | 2000-01-05 | — | — | EP | claimed |