Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 6/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019235 | 0.82 | GABRG2 (0.37) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL8030562 | 0.82 | GABRG2 (0.39) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL13002475 | 0.81 | GABRG2 (0.57) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| Trifluoroacetic Acid SCHEMBL3765321 | 0.79 | GABRG2 (0.52) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL8028116 | 0.78 | GABRG2 (0.32) | GABRG2GABRB3GABRA3 | |
| SCHEMBL13002478 | 0.77 | NOTUM (0.40) | MYCPKMTSHR | |
| SCHEMBL13059442 | 0.77 | GABRG2 (0.45) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL9263923 | 0.75 | GABRG2 (0.42) | GABRG2GABRB3GABRA3MYCGABRA5 | |
| SCHEMBL12196276 | 0.74 | GABRG2 (0.32) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL1311760 | 0.69 | GABRG2 (0.42) | GABRG2GABRB3GABRA3MYCGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250157-B1 | NOVEL HETEROCYCLIC COMPOUNDS | PANACEA BIOTEC LTD (IN) | 2014-11-05 | — | — | EP | disclosed |
| US-8455479-B2 | Heterocyclic compounds | PANACEA BIOTEC LIMITED (IN) | 2013-06-04 | — | — | US | disclosed |
| WO-2009093269-A1 | NOVEL HETEROCYCLIC COMPOUNDS | PANACEA BIOTEC LIMITED (IN) | 2009-07-30 | — | — | WO | disclosed |