Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276341 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL8018005 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL8019780 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL8020118 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL8017766 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL3798118 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL8018301 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL8019785 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL8021590 | 1.00 | OPRM1 (0.48) | OPRM1TSHRTHRBLMNADNM1 | |
| SCHEMBL1125778 | 0.97 | OPRM1 (0.50) | OPRM1TSHRTHRBLMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002536-A2 | 2-Amino, 4-alkylamino pyrimidine 3-oxydes as soothing agents for the skin | L'OREAL (FR) | 2000-05-24 | — | — | EP | claimed |
| EP-0974586-A1 | 2-amino-4-alkylamino-pyrimidine 3-oxydes and compositions containing same | L'OREAL (FR) | 2000-01-26 | — | — | EP | claimed |
| EP-1002536-A2 | 2-Amino, 4-alkylamino pyrimidine 3-oxydes as soothing agents for the skin | L'OREAL (FR) | 2000-05-24 | — | — | EP | disclosed |
| EP-0974586-A1 | 2-amino-4-alkylamino-pyrimidine 3-oxydes and compositions containing same | L'OREAL (FR) | 2000-01-26 | — | — | EP | disclosed |