Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31515627 | 0.84 | KMT2A (0.49) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL9803 | 0.84 | KMT2A (0.49) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL260819 | 0.82 | MEN1 (0.47) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL31244372 | 0.82 | MEN1 (0.47) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL29574672 | 0.80 | MEN1 (0.46) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL7999641 | 0.80 | KMT2A (0.46) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL28537450 | 0.80 | KMT2A (0.46) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL8984873 | 0.80 | KMT2A (0.51) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL3396632 | 0.80 | KMT2A (0.46) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL8105501 | 0.80 | KMT2A (0.46) | KMT2AMEN1ESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704450-B1 | Novel sulfonated phosphines, process for their preparation and their use as constituents of catalyst systems | CELANESE CHEM EUROPE GMBH (DE) | 2000-01-26 | — | — | EP | disclosed |
| US-5780674-A | SULFONATION OF PHOSPHINE COMPOUNDS WITH SULFURIC ACID OR A MIXTURE OF SULFURIC ACID AND ORTHOBORIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |