Sugi Predict

Sugi Predict / Compounds / SCHEMBL9803

SCHEMBL9803

SCHEMBL9803

Cc1ccccc1S(=O)(=O)OS(=O)(=O)c1ccccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ ESR1 P03372 2/20 0.49
▸ ESR2 Q92731 2/20 0.49
▸ GAA P10253 1/20 0.49
▸ POLB P06746 1/20 0.47
▸ ALDH1A1 P00352 6/20 0.46
▸ ATM Q13315 1/20 0.46
▸ CYP1A2 P05177 1/20 0.45
▸ CYP2C9 P11712 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ TSHR P16473 1/20 0.41
▸ ACHE P22303 1/20 0.41
▸ HTR6 P50406 1/20 0.41
▸ RAPGEF4 Q8WZA2 1/20 0.41
▸ KDM4E B2RXH2 3/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ TP53 P04637 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31515627 1.00 KMT2A (0.49) KMT2AMEN1ESR1ESR2GAA
SCHEMBL31244372 0.84 MEN1 (0.47) KMT2AMEN1ESR1ESR2GAA
SCHEMBL260819 0.84 MEN1 (0.47) KMT2AMEN1ESR1ESR2GAA
SCHEMBL8019502 0.84 KMT2A (0.47) KMT2AMEN1ESR1ESR2GAA
SCHEMBL29574672 0.82 MEN1 (0.46) KMT2AMEN1ESR1ESR2GAA
SCHEMBL6113036 0.82 KMT2A (0.44) KMT2AMEN1ESR1ESR2GAA
SCHEMBL28537450 0.82 KMT2A (0.46) KMT2AMEN1ESR1ESR2GAA
SCHEMBL3396632 0.82 KMT2A (0.46) KMT2AMEN1ESR1ESR2GAA
SCHEMBL8984873 0.82 KMT2A (0.51) KMT2AMEN1ESR1ESR2GAA
SCHEMBL7999641 0.82 KMT2A (0.46) KMT2AMEN1ESR1ESR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1013 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215003-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB GRANULES INDIA LIMITED (IN) 2025-07-03 — — US claimed
CN-119032095-A Improved process for preparing ruxolitinib 印度颗粒有限公司 2024-11-26 — — CN claimed
EP-4463460-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB Granules India Limited (IN) 2024-11-20 — — EP claimed
EP-4444293-A2 METHODS OF PREPARING SUBSTITUTED PYRAZOLOPYRIMIDINES KSQ Therapeutics, Inc. (US) 2024-10-16 — — EP claimed
CN-115884974-B Process for preparing alkyl 7-amino-5-methyl- [1,2,5] oxadiazolo [3,4-b ] pyridinecarboxylic acid esters 勃林格殷格翰国际有限公司 2024-09-17 — — CN claimed
EP-4153600-B1 CONTINUOUS PROCESS FOR MANUFACTURING ALKYL 7-AMINO-5-METHYL-[1,2,5]OXADIAZOLO[3,4-B]PYRIDINE-CARBOXYLATE BOEHRINGER INGELHEIM INT (DE) 2024-08-07 — — EP claimed
CN-118369094-A Process for preparing substituted pyrazolopyrimidines KSQ治疗公司 2024-07-19 — — CN claimed
US-11976082-B2 Continuous process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-05-07 — — US claimed
EP-4153599-B1 PROCESS FOR MANUFACTURING ALKYL 7-AMINO-5-METHYL-[1,2,5]OXADIAZOLO[3,4-B]PYRIDINE-CARBOXYLATE BOEHRINGER INGELHEIM INT (DE) 2024-03-13 — — EP claimed
WO-2024042448-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB GRANULES INDIA LIMITED (IN) 2024-02-29 — — WO claimed
WO-2007039918-A1 NOVEL PROCESS FOR THE PREPARATION OF TOLTERODINE NATCO PHARMA LIMITED (IN) 2007-04-12 — — WO claimed
WO-2006036498-A2 A PROCESS FOR THE PREPARATION OF 1,3,5-TRISUBSTITUTED PYRAZOLES VIA [3+2] CYCLOADDITION BRISTOL-MYERS SQUIBB COMPANY (US) 2006-04-06 — — WO claimed
US-20060069270-A1 Process for the preparation of 1,3,5-trisubstituted pyrazoles via [3+2] cycloaddition BRISTOL-MYERS SQUIBB COMPANY 2006-03-30 — — US claimed
EP-1453809-A1 PROCESS FOR THE PREPARATION OF 4-METHYL-7-AMINOQUINOLONES Ciba SC Holding AG (CH) 2004-09-08 — — EP claimed
WO-2003050089-A1 PROCESS FOR THE PREPARATION OF 4-METHYL-7-AMINOQUINOLONES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-06-19 — — WO claimed
EP-1274681-A1 PROCESS FOR PRODUCING AMIDE COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2003-01-15 — — EP claimed
US-6464773-B1 Toluene sulfonic acid swelling of perylene pigments SUN CHEMICAL CORPORATION 2002-10-15 — — US claimed
WO-2002048267-A2 TOLUENE SULFONIC ACID SWELLING OF PERYLENE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (US) 2002-06-20 — — WO claimed
WO-2001081302-A1 PROCESS FOR PRODUCING AMIDE COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2001-11-01 — — WO claimed
US-5087773-A Reacting with toluenesulfonic anhydride, contacting with telluride or selenide SYRACUSE UNIVERSITY (US) 1992-02-11 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215003-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB JAK1, JAK3, JAK2 KMT2A 805/4885MEN1 3099/4885ESR1 3791/4885
US-11976082-B2 Continuous process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate ALKBH5, ALKBH3, MMAB KMT2A 601/4885MEN1 4067/4885ESR1 4288/4885
US-20060069270-A1 Process for the preparation of 1,3,5-trisubstituted pyrazoles via [3+2] cycloaddition TFPI, F2, F11 KMT2A 4252/4885MEN1 506/4885ESR1 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.