Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019596 | 1.00 | PPARA (0.46) | PPARAPPARGHTTMAPTMAPK1 | |
| SCHEMBL28354766 | 0.92 | HTT (0.49) | PPARAPPARGHTTMAPTMAPK1 | |
| SCHEMBL9239878 | 0.92 | HTT (0.49) | PPARAPPARGHTTMAPTMAPK1 | |
| SCHEMBL8019591 | 0.91 | HTT (0.48) | PPARAPPARGHTTMAPTMAPK1 | |
| SCHEMBL31290840 | 0.86 | HTT (0.45) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL2715741 | 0.86 | HTT (0.45) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL11023824 | 0.85 | HTT (0.42) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL28739184 | 0.85 | PPARA (0.48) | PPARAPPARG | |
| SCHEMBL10730145 | 0.84 | HTT (0.49) | PPARAPPARGHTTMAPTMAPK1 | |
| SCHEMBL10411644 | 0.83 | F7 (0.43) | PPARAPPARGMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157969-B2 | Organo-borate compositions and their use in lubricants | LUBRIZOL CORP (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0157969-A1 | Organo-borate compositions and their use in lubricants | The Lubrizol Corporation (US) | 1985-10-16 | — | — | EP | disclosed |
| US-3959159-A | Nitrogen-containing mixed esters and lubricants | THE LUBRIZOL CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
| US-3956149-A | CARBOXY-CONTAINING COPOLYMER | THE LUBRIZOL CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |