Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858425 | 0.87 | SLC6A4 (0.58) | SLC6A4SLC6A2GBA1SLC6A3CHRM2 | |
| SCHEMBL23842753 | 0.83 | P2RX7 (0.44) | SLC6A4SLC6A2ALDH1A1SLC6A3 | |
| SCHEMBL1322888 | 0.83 | SLC6A4 (0.61) | SLC6A4SLC6A2GBA1SLC6A3MAPK1 | |
| SCHEMBL3962949 | 0.83 | SLC6A4 (0.51) | SLC6A4SLC6A2GBA1SLC6A3MAPK1 | |
| Hydrochloric Acid SCHEMBL4772849 | 0.82 | SLC6A4 (0.60) | SLC6A4SLC6A2GBA1SLC6A3MAPK1 | |
| Hydrochloric Acid SCHEMBL23830968 | 0.82 | P2RX7 (0.43) | SLC6A4SLC6A2ALDH1A1SLC6A3 | |
| SCHEMBL21788553 | 0.81 | SLC6A4 (0.58) | SLC6A4SLC6A2GBA1SLC6A3MAPK1 | |
| SCHEMBL31071558 | 0.80 | SLC6A4 (0.49) | SLC6A4SLC6A2GBA1SLC6A3MAPK1 | |
| SCHEMBL3970684 | 0.80 | SLC6A4 (0.61) | SLC6A4SLC6A2GBA1SLC6A3MAPK1 | |
| SCHEMBL22265871 | 0.80 | SLC6A4 (0.47) | SLC6A4SLC6A2GBA1SLC6A3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |