Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126489 | 0.90 | SIGMAR1 (0.69) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL1394535 | 0.77 | KDM4E (0.68) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL1394539 | 0.77 | KDM4E (0.68) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL1394677 | 0.77 | KDM4E (0.68) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL23775274 | 0.77 | SIGMAR1 (0.64) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL24672242 | 0.77 | KDM4E (0.68) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL8446786 | 0.77 | SIGMAR1 (0.64) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL8446462 | 0.77 | SIGMAR1 (0.64) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL21797152 | 0.77 | KDM4E (0.68) | SIGMAR1MC4RKDM4ELMNAPOLB | |
| SCHEMBL10885924 | 0.77 | SIGMAR1 (0.64) | SIGMAR1MC4RKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |