Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055718 | 1.00 | OPRM1 (0.46) | OPRM1CXCL8RORCTP53CASP1 | |
| Hydrochloric Acid SCHEMBL4846464 | 0.99 | OPRM1 (0.45) | OPRM1CXCL8RORCTP53CASP1 | |
| SCHEMBL1160304 | 0.86 | OPRM1 (0.43) | OPRM1RORCCASP1NR1H2NR1H3 | |
| SCHEMBL1417521 | 0.86 | OPRM1 (0.43) | OPRM1RORCCASP1NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL28361730 | 0.85 | OPRM1 (0.42) | OPRM1RORCCASP1NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL1159843 | 0.85 | OPRM1 (0.42) | OPRM1RORCCASP1NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL1159973 | 0.85 | OPRM1 (0.42) | OPRM1RORCCASP1NR1H2NR1H3 | |
| SCHEMBL1609792 | 0.83 | OPRM1 (0.38) | OPRM1RORCTP53CASP1TRPM8 | |
| Hydrochloric Acid SCHEMBL28361713 | 0.81 | OPRM1 (0.48) | OPRM1TRPM8 | |
| Hydrochloric Acid SCHEMBL1419666 | 0.81 | OPRM1 (0.37) | OPRM1RORCCASP1TRPM8CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971915-A1 | METHOD FOR PREPARING 2-THIENYLETHYLAMINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998039322-A1 | METHOD FOR PREPARING 2-THIENYLETHYLAMINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 1998-09-11 | — | — | WO | disclosed |