Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 12/20 | 0.43 |
| ▸ | PPARA | Q07869 | 11/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020188 | 0.92 | NPC1 (0.45) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8020194 | 0.92 | NPC1 (0.45) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8024500 | 0.89 | PPARG (0.46) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8026206 | 0.88 | PPARG (0.45) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8067505 | 0.83 | PPARG (0.45) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8067509 | 0.83 | PPARG (0.45) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8026087 | 0.82 | PPARG (0.50) | NPC1RAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL8023039 | 0.82 | PPARG (0.48) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8023037 | 0.82 | PPARG (0.48) | NPC1RAB9APPARGPPARAS1PR1 | |
| SCHEMBL8019905 | 0.81 | PPARG (0.45) | NPC1RAB9APPARGPPARAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975587-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998043949-A1 | OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-08 | — | — | WO | disclosed |