SCHEMBL8026087

SCHEMBL8026087

CC=C(Oc1cccc(C(C)=NOCc2ccccc2)c1)C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.50
PPARA Q07869 11/20 0.50
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
HIF1A Q16665 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAOB P27338 1/20 0.45
HPGD P15428 1/20 0.42
NR4A2 P43354 1/20 0.41
SMPD1 P17405 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8026084 0.92 PPARG (0.48) PPARGPPARANPC1RAB9AHIF1A
SCHEMBL8024500 0.83 PPARG (0.46) PPARGPPARANPC1RAB9ASMN1; SMN2
SCHEMBL8026206 0.82 PPARG (0.45) PPARGPPARANPC1RAB9ASMN1; SMN2
SCHEMBL8020195 0.82 NPC1 (0.47) PPARGPPARANPC1RAB9ASMN1; SMN2
SCHEMBL8026284 0.77 NPC1 (0.54) NPC1RAB9ASMN1; SMN2L3MBTL1MAOB
SCHEMBL8020436 0.77 PPARG (0.48) PPARGPPARANPC1RAB9AHIF1A
SCHEMBL8023039 0.76 PPARG (0.48) PPARGPPARANPC1RAB9ASMN1; SMN2
SCHEMBL8023037 0.76 PPARG (0.48) PPARGPPARANPC1RAB9ASMN1; SMN2
SCHEMBL8067505 0.75 PPARG (0.45) PPARGPPARANPC1RAB9ASMN1; SMN2
SCHEMBL8067509 0.75 PPARG (0.45) PPARGPPARANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975587-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
WO-1998043949-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-08 WO disclosed