Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363539 | 0.87 | USP30 (0.48) | STSKDM4EPKMGNRHRGPR119 | |
| SCHEMBL9947231 | 0.78 | NAMPT (0.47) | STSKDM4EGPR119MAPTTHRB | |
| SCHEMBL8026194 | 0.78 | GRM5 (0.38) | STSGPR119 | |
| SCHEMBL1363304 | 0.76 | KDM4E (0.51) | STSKDM4EPKMGPR119LMNA | |
| SCHEMBL12720747 | 0.75 | DDB1 (0.47) | GPR119 | |
| SCHEMBL18617673 | 0.75 | KDM4E (0.52) | STSKDM4EPKMGPR119LMNA | |
| SCHEMBL3375291 | 0.75 | USP30 (0.53) | KDM4EPKMGNRHRGPR119LMNA | |
| SCHEMBL3161476 | 0.74 | SMN1; SMN2 (0.58) | STSKDM4EPKMGPR119LMNA | |
| SCHEMBL16113771 | 0.74 | GPR119 (0.61) | STSKDM4EPKMGPR119LMNA | |
| SCHEMBL14852116 | 0.74 | GPR119 (0.51) | STSKDM4EPKMGPR119LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100168-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009100166-A1 | DUAL PHARMACOPHORES-PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |