Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030291 | 0.95 | KMT2A (0.39) | KMT2AMEN1GAAITGB1ITGA4 | |
| SCHEMBL8034120 | 0.95 | KMT2A (0.40) | KMT2AMEN1GAAITGB1ITGA4 | |
| SCHEMBL8033880 | 0.95 | KMT2A (0.44) | KMT2AMEN1GAAITGB1ITGA4 | |
| SCHEMBL8029977 | 0.94 | KMT2A (0.38) | KMT2AMEN1GAAITGB1ITGA4 | |
| SCHEMBL8033932 | 0.94 | KMT2A (0.39) | KMT2AMEN1GAAITGB1ITGA4 | |
| SCHEMBL8020734 | 0.92 | KMT2A (0.40) | KMT2AMEN1GAAITGB1ITGA4 | |
| SCHEMBL8030352 | 0.92 | KMT2A (0.40) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL8032277 | 0.92 | KMT2A (0.40) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL27489100 | 0.91 | KMT2A (0.37) | KMT2AMEN1GAAITGB1ITGA4 | |
| SCHEMBL8020736 | 0.90 | ITGB1 (0.36) | KMT2AMEN1GAAITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |