Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030646 | 0.95 | KMT2A (0.36) | ITGB1ITGA4SMN1; SMN2PDE5AMAPK1 | |
| SCHEMBL8020589 | 0.94 | SMN1; SMN2 (0.35) | ITGB1ITGA4SMN1; SMN2MAPK1PPIB | |
| SCHEMBL8020901 | 0.94 | SMN1; SMN2 (0.37) | ITGB1ITGA4SMN1; SMN2PDE5AMAPK1 | |
| SCHEMBL8020758 | 0.93 | KMT2A (0.37) | SMN1; SMN2PDE5AMAPK1PPIBHTT | |
| SCHEMBL27475959 | 0.91 | MLYCD (0.34) | ITGB1ITGA4SMN1; SMN2MAPK1PPIB | |
| SCHEMBL8029961 | 0.91 | KMT2A (0.38) | SMN1; SMN2MAPK1HTTNPC1KMT2A | |
| SCHEMBL8031868 | 0.91 | PPIB (0.38) | SMN1; SMN2PDE5AMAPK1PPIBHTT | |
| SCHEMBL8031875 | 0.91 | MAPK1 (0.40) | SMN1; SMN2PDE5AMAPK1HTTKMT2A | |
| SCHEMBL8020517 | 0.90 | KMT2A (0.40) | ITGB1ITGA4SMN1; SMN2MAPK1PPIB | |
| SCHEMBL8020628 | 0.90 | KMT2A (0.42) | SMN1; SMN2HTTNPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |