Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.41 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030394 | 0.94 | CASR (0.46) | RAB9ASMN1; SMN2BDKRB2CASRKMT2A | |
| SCHEMBL8030189 | 0.93 | BDKRB2 (0.39) | NPC1RAB9ASMN1; SMN2MITFPAX8 | |
| SCHEMBL8029986 | 0.89 | KMT2A (0.40) | SMN1; SMN2CASRKMT2AMEN1GAA | |
| SCHEMBL8036249 | 0.88 | NR1H4 (0.41) | NPC1RAB9ASMN1; SMN2MITFPAX8 | |
| SCHEMBL8030209 | 0.88 | CASR (0.36) | SMN1; SMN2CASRKMT2AMEN1GAA | |
| SCHEMBL8031801 | 0.87 | CASR (0.42) | NPC1RAB9ASMN1; SMN2BDKRB2CASR | |
| SCHEMBL8030284 | 0.86 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2MITFPAX8 | |
| SCHEMBL8036739 | 0.84 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2MITFPAX8 | |
| SCHEMBL8030202 | 0.84 | BDKRB2 (0.42) | NPC1RAB9ASMN1; SMN2MITFPAX8 | |
| SCHEMBL8030205 | 0.83 | CASR (0.42) | NPC1RAB9ASMN1; SMN2MITFPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |