Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019119 | 0.85 | SRD5A2 (0.56) | SRD5A2SRD5A1AR | |
| SCHEMBL8023090 | 0.84 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL8084464 | 0.83 | SRD5A2 (0.63) | SRD5A2SRD5A1AR | |
| SCHEMBL8084466 | 0.83 | SRD5A2 (0.63) | SRD5A2SRD5A1AR | |
| SCHEMBL8020698 | 0.81 | SRD5A1 (0.53) | SRD5A2SRD5A1AR | |
| SCHEMBL8020976 | 0.81 | SRD5A1 (0.58) | SRD5A2SRD5A1 | |
| SCHEMBL8019047 | 0.80 | SRD5A2 (0.51) | SRD5A2SRD5A1AR | |
| SCHEMBL8023773 | 0.79 | SRD5A1 (0.54) | SRD5A2SRD5A1 | |
| SCHEMBL8016224 | 0.78 | SRD5A1 (0.61) | SRD5A2SRD5A1AR | |
| SCHEMBL8710566 | 0.78 | SRD5A1 (0.55) | SRD5A2SRD5A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664812-B1 | 17-BETA-ARYL ESTER CARBOXYLATES OF 4-AZA-5-ALPHA-ANDROSTANE-3-ONES | MERCK & CO INC (US) | 2000-01-05 | — | — | EP | claimed |