Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471182 | 0.98 | REN (0.51) | REN | |
| SCHEMBL3420342 | 0.98 | REN (0.51) | REN | |
| SCHEMBL13030791 | 0.96 | REN (0.49) | REN | |
| SCHEMBL3413306 | 0.96 | REN (0.49) | REN | |
| SCHEMBL3079010 | 0.96 | REN (0.49) | REN | |
| SCHEMBL13030792 | 0.96 | REN (0.49) | REN | |
| SCHEMBL13030764 | 0.95 | REN (0.47) | REN | |
| SCHEMBL3072197 | 0.95 | REN (0.47) | REN | |
| SCHEMBL13030790 | 0.95 | REN (0.47) | REN | |
| SCHEMBL3084868 | 0.95 | REN (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121914-A1 | SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 2009-10-08 | — | — | WO | disclosed |
| EP-1911758-A1 | Phenyl piperidine derivatives for use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |