Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10165338 | 1.00 | CHRM2 (0.46) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL8018904 | 0.93 | CHRM2 (0.50) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL16617834 | 0.93 | CHRM2 (0.46) | CHRM2CHRM4CHRM3CYP3A4 | |
| SCHEMBL8008302 | 0.93 | CHRM2 (0.46) | CHRM2CHRM4CHRM3CYP3A4 | |
| SCHEMBL19818356 | 0.91 | CHRM2 (0.44) | CHRM2CHRM4CHRM3 | |
| SCHEMBL16131620 | 0.91 | CHRM2 (0.44) | CHRM2CHRM4CHRM3 | |
| SCHEMBL8226507 | 0.89 | CHRM2 (0.52) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL2965074 | 0.89 | CHRM2 (0.52) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL8355491 | 0.89 | CHRM2 (0.52) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL2742462 | 0.89 | CHRM2 (0.52) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |